RAF Typhoon FGR4s have operated alongside French warplanes in a combined operation against an subterranean weapons facility in Syrian territory operated by the Islamic State group (IS), according to the UK Ministry of Defence.
The site, located using reconnaissance, was thought to be containing munitions and bombs, the announcement noted, and was positioned in mountains just north of the ancient city of Palmyra in Syria's central region.
"Our aircraft utilized precision-guided Paveway IV munitions to strike a number of approach shafts down to the depot... early reports are that the target was engaged successfully," officials stated.
There was no indication of any civilian impact in the operation late on Saturday and each participating jet returned safely, the MoD added.
The Typhoon FGR4s were assisted by a Voyager aerial refuelling aircraft.
Daesh - alternatively referred to as the so-called Islamic State - established jihadist rule over significant areas in both Syria and Iraq prior to its 2019 collapse.
"This operation demonstrates the UK's leading role, and resolve to operate in unison with allied nations, to eradicate any resurgence of IS and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief the minister said.
UK warplanes have carried out patrols over Syrian airspace to "deter any attempted resurgence" of the group following its defeat at the Baghuz confrontation in 2019, the ministry said.
"I must thank the personnel of our armed forces participating in this mission for their skill and their bravery," the Defence Secretary commented. "Including them were a great many British troops stationed over the festive period. This mission, to take out militants who endanger our security, demonstrates how UK forces are ready to step up, continuously, ensuring Britain's security at home and influential overseas."
During December, the United States armed forces executed what it called a "large-scale strike" on Daesh sites in Syria, subsequent to an attack resulted in the deaths of two American soldiers and a civilian linguist in Palmyra.
The UN estimates Islamic State still has between 5,000 and 7,000 militants in Iraq and Syria.